Effects of tDCS and intensive behavioral therapy in a longevous individual with low education and subacute aphasia

Natália Callegaro Costa; Rafaela Rossini Peters; Pamela Lemes Rocha; Karina Carlesso Pagliarin

doi:10.1590/2317-1782/e20240304en

Case Report

Effects of tDCS and intensive behavioral therapy in a longevous individual with low education and subacute aphasia

Natália Callegaro Costa; Rafaela Rossini Peters; Pamela Lemes Rocha; Karina Carlesso Pagliarin

http://dx.doi.org/10.1590/2317-1782/e20240304en CoDAS, vol.38, n1, e20240304, 2026

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Abstract

ABSTRACT: The aim of this study was to examine the effects of tDCS during intensive word-finding therapy on subacute aphasia after stroke. A single-case study with an 86-year-old man with four years of formal education, diagnosed with an ischemic stroke in the left hemisphere, resulting in non-fluent aphasia of the mixed type, accompanied by acquired apraxia of speech. For this purpose, the Montreal-Toulouse Language Assessment Battery - Brief Version was administered at five different time points: (A1) one week before the start of treatment; (A2) after the first session; (A3) after five sessions; (A4) after ten sessions and; (A5) after 30 days without intervention. The Naming and Visual Recognition Test was also administered at points A1, A4 and A5. After the intervention, improvements were noted in word naming and verbal word comprehension. There was a reduction in linguistic errors such as paraphasias. These results support the combination of tDCS and behavioral training.

Keywords

Transcranial Direct Current Stimulation, Stroke, Speech Therapy, Aphasia, Speech

References

1 Berg K, Isaksen J, Wallace SJ, Cruice M, Simmons-Mackie N, Worrall L. Establishing consensus on a definition of aphasia: an e-Delphi study of international aphasia researchers. Aphasiology. 2020;36(4):1-16. https://doi.org/10.1080/02687038.2020.1852003.

2 Kiran S, Thompson CK. Neuroplasticity of language networks in aphasia: advances, updates, and future challenges. Front Neurol. 2019;10:295. https://doi.org/10.3389/fneur.2019.00295. PMid:31001187.

3 Python G, Pellet Cheneval P, Bonnans C, Laganaro M. Facilitating word retrieval in aphasia: which type of cues for which aphasic speakers? Front Hum Neurosci. 2021;15:747391. https://doi.org/10.3389/fnhum.2021.747391. PMid:34899216.

4 Figeys M, Kim ES, Hopper T. Does right-hemispheric anodal tDCS enhance the impact of script training in chronic aphasia? a single-subject experimental study. Front Rehabil Sci. 2022;2:793451. https://doi.org/10.3389/fresc.2021.793451. PMid:36188817.

5 Campanella W, Pedrini R, Vestito L, Marinelli L, Trompetto C, Mori L. Transcranial direct current stimulation in the treatment of subacute post-stroke thalamic aphasia. Eur J Case Rep Intern Med. 2020;7(11):001794. https://doi.org/10.12890/2020_001794. PMid:33194851.

6 Spielmann K, van de Sandt-Koenderman WM, Heijenbrok-Kal MH, Ribbers GM. Transcranial direct current stimulation in post-stroke sub-acute aphasia: study protocol for a randomized controlled trial. Trials. 2016;17(1):380. https://doi.org/10.1186/s13063-016-1505-z. PMid:27484456.

7 Meinzer M, Darkow R, Lindenberg R, Flöel A. Electrical stimulation of the motor cortex enhances treatment outcome in post-stroke aphasia. Brain. 2016;139(Pt 4):1152-63. https://doi.org/10.1093/brain/aww002. PMid:26912641.

8 Biou E, Cassoudesalle H, Cogné M, Sibon I, De Gabory I, Dehail P, et al. Transcranial direct current stimulation in post-stroke aphasia rehabilitation: A systematic review. Ann Phys Rehabil Med. 2019;62(2):104-21. https://doi.org/10.1016/j.rehab.2019.01.003. PMid:30660671.

9 Busby N, Wilmskoetter J, Gleichgerrcht E, Rorden C, Roth R, Newman-Norlund R, et al. Advanced brain age and chronic poststroke aphasia severity. Neurology. 2023;100(11):e1166-76. https://doi.org/10.1212/WNL.0000000000201693. PMid:36526425.

10 Gomes I, Ferreira I. Em 2022, analfabetismo cai, mas continua mais alto entre idosos, pretos e pardos e no Nordeste [Internet]. Rio de Janeiro: Agência de Notícias IBGE; 2023 [cited 2024 Sept 24]. Available from: https://agenciadenoticias.ibge.gov.br/agencia-noticias/2012-agencia-de-noticias/noticias/37089-em-2022-analfabetismo-cai-mas-continua-mais-alto-entre-idosos-pretos-e-pardos-e-no-nordeste.

11 Connor LT, Obler LK, Tocco M, Fitzpatrick PM, Albert ML. Effect of socioeconomic status on aphasia severity and recovery. Brain Lang. 2001;78(2):254-7. https://doi.org/10.1006/brln.2001.2459. PMid:11500074.

12 Torres J, Drebing D, Hamilton R. TMS and tDCS in post-stroke aphasia: integrating novel treatment approaches with mechanisms of plasticity. Restor Neurol Neurosci. 2013;31(4):501-15. https://doi.org/10.3233/RNN-130314. PMid:23719561.

13 Fonseca RP, Zimmermann N, Pawlowski J, Oliveira CR, Gindri G, Scherer LC, et al. Métodos em avaliação neuropsicológica. In: Landeira-Fernandez J, Fukusima SS, editors. Métodos em avaliação neuropsicológica. 1. ed. Barueri: Manole; 2012. p. 266-96.

14 Altmann RF, Ortiz KZ, Benfica TR, Oliveira EP, Pagliarin KC. Brief Montreal-Toulouse Language Assessment Battery: adaptation and content validity. Psicol Reflex Crit. 2020;33(1):18. https://doi.org/10.1186/s41155-020-00157-6. PMid:32734309.

15 Zimmermann N, Fonseca RP, Delaere FJ. Teste de nomeação e de reconhecimento visual. In: Zimmermann N, Delaere FJ, Fonseca RP, editors. Avaliação de memória episódica, percepção, linguagem e componentes executivos para adultos. São Paulo: Memnon; 2019. (Tarefas para Avaliação Neuropsicológica, Vol. 3).

16 Kendall D, Raymer A, Rose M, Gilbert J, Gonzalez Rothi LJ. Anomia treatment platform as behavioral engine for use in research on physiological adjuvants to neurorehabilitation. J Rehabil Res Dev. 2014;51(3):391-400. https://doi.org/10.1682/JRRD.2013.08.0172. PMid:25019662.

17 Linebaugh CW, Shisler RJ, Lehner L. CAC classics. Aphasiology. 2005;19(1):77-92. https://doi.org/10.1080/02687030444000363.

18 Marangolo P, Fiori V, Cipollari S, Campana S, Razzano C, Di Paola M, et al. Bihemispheric stimulation over left and right inferior frontal region enhances recovery from apraxia of speech in chronic aphasia. Eur J Neurosci. 2013;38(9):3370-7. https://doi.org/10.1111/ejn.12332. PMid:23930827.

19 Aguiar V, Bastiaanse R, Capasso R, Gandolfi M, Smania N, Rossi G, et al. Can tDCS enhance item-specific effects and generalization after linguistically motivated aphasia therapy for verbs? Front Behav Neurosci. 2015;9:190. https://doi.org/10.3389/fnbeh.2015.00190. PMid:26903832.

20 Cid-Fernández S, Rivas-Fernández MÁ, Varela-López B, Galdo-Álvarez S. Combined anodal transcranial direct current stimulation and behavioural naming treatment improves language performance in patients with post-stroke aphasia. Brain Inj. 2022;36(8):1039-45. https://doi.org/10.1080/02699052.2022.2109733. PMid:35949195.

21 Martins VO, Andrade CRF. Estudo das pausas em idosos. Rev Soc Bras Fonoaudiol. 2011;16(3):344-9. https://doi.org/10.1590/S1516-80342011000300017.

Submitted date:
09/24/2024

Accepted date:
06/30/2025

Effects of tDCS and intensive behavioral therapy in a longevous individual with low education and subacute aphasia

Natália Callegaro Costa; Rafaela Rossini Peters; Pamela Lemes Rocha; Karina Carlesso Pagliarin

Abstract

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