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http://www.codas.periodikos.com.br/article/doi/10.1590/2317-1782/e20250002pt
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Systematic Review

Efeitos da Estimulação Transcraniana por Corrente Contínua nas alterações de Fala e Voz para a Doença de Parkinson: uma Revisão Sistemática com Metanálise

Effects of Transcranial Direct Current Stimulation on Speech and Voice Changes in Parkinson’s Disease: a Systematic Review with Meta-Analysis

Renata Serrano de Andrade Pinheiro; Hercílio Barbosa da Silva Júnior; Bruno Braga Guimarães; Ivonaldo Leidson Barbosa Lima; Rafael Nóbrega Bandeira; Nelson Torro Alves

http://dx.doi.org/10.1590/2317-1782/e20250002pt CoDAS, vol.38, n1, e20250002, 2026
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Resumo

RESUMO: Objetivo: Esta metanálise tem o objetivo de avaliar a evidência existente dos efeitos da tDCS nas alterações de fala e de voz de pacientes com DP.

Estratégias de Pesquisa: PubMed, LILACS, EMBASE, Cochrane Central Register of Controlled Trials, Science Direct, Web of Science, Scopus e de literatura cinzenta Google Scholar e Open Grey. A busca incluiu os descritores: “Parkinson Disease, Transcranial Direct Current Stimulation, Voice, Speech” combinados com AND e OR.

Critérios de Seleção: Pacientes com a Doença de Parkinson, ambos os sexos. Uso da Estimulação Transcraniana por Corrente Contínua (tDCS) para tratar os parâmetros de voz e fala nos pacientes acometidos pela Doença de Parkinson.

Análise de dados: Um total de 1.345 artigos, 14 artigos incluídos na revisão sistemática e 6 artigos na metanálise. O risco de viés e o nível de evidência foram avaliados pelo software REVIEW MANAGER 5.4.1. e GRADE.

Resultados: Os resultados mostraram um tamanho de efeito geral da tDCS de Z= 0.89 (P=0.37). Estudos com área alvo no córtex pré-frontal (PFC) apresentaram maior tamanho de efeito 1.38(P=0.17), portanto com maior impacto para desfecho de fala e voz com uso de tDCS para DP. Três estudos apresentaram baixo risco de viés e três estudos apresentaram risco pouco claro.

Conclusão: Apesar do baixo número de estudos, os achados desta metanálise sugerem a potencial aplicabilidade da tDCS como ferramenta adjuvante no tratamento das alterações de voz e fala em pacientes com DP.

Palavras-chave

Doença de Parkinson, Estimulação Transcraniana por Corrente Contínua, Voz, Qualidade Vocal, Fala

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Submitted date:
01/06/2025

Accepted date:
06/25/2025

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